Apolipoprotein (a) alleles determine lipoprotein (a) particle density and concentration in plasma.

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Apolipoprotein (a) alleles determine lipoprotein (a) particle density and concentration in plasma.

The distribution of Lp(a) lipoprotein (Lp[a]) and genetic apolipoprotein(a) (apo[a]) isoforms in plasma samples from 29 healthy normolipidemic subjects of known apo(a) phenotype was evaluated by density gradient ultracentrifugation. The density of Lp(a) was directly related to the size of the apo(a) isoform, ranging from 1.043 g/ml for the LpF phenotype to 1.114 g/ml for the LpS4 phenotype. Het...

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ژورنال

عنوان ژورنال: Arteriosclerosis and Thrombosis: A Journal of Vascular Biology

سال: 1992

ISSN: 1049-8834

DOI: 10.1161/01.atv.12.3.302